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Experimental Models of Inherited PrP Prion Diseases

The inherited prion protein (PrP) prion disorders, which include familial Creutzfeldt–Jakob disease, Gerstmann–Sträussler–Scheinker disease, and fatal familial insomnia, constitute ∼10%–15% of all PrP prion disease cases in humans. Attempts to generate animal models of these disorders using transgen...

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Bibliografiske detaljer
Udgivet i:Cold Spring Harb Perspect Med
Main Authors: Watts, Joel C., Prusiner, Stanley B.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5513788/
https://ncbi.nlm.nih.gov/pubmed/28096244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a027151
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