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Central Regulatory Role for SIN1 in Interferon γ (IFNγ) Signaling and Generation of Biological Responses
The precise signaling mechanisms by which type II IFN receptors control expression of unique genes to induce biological responses remain to be established. We provide evidence that Sin1, a known element of the mammalian target of rapamycin complex 2 (mTORC2), is required for IFNγ-induced phosphoryla...
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Publicado no: | J Biol Chem |
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Main Authors: | , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Biochemistry and Molecular Biology
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5377787/ https://ncbi.nlm.nih.gov/pubmed/28174303 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.757666 |
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