IFNγ-inducible antiviral responses require ULK1-mediated activation of MLK3 and ERK5

It is well established that activation of the transcription factor signal transducer and activator of transcription 1 (STAT1) is required for the interferon-γ (IFN-γ)–mediated antiviral response. Here, we found that IFN-γ receptor stimulation also activated Unc-51-like kinase 1 (ULK1), an initiator...

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Detalhes bibliográficos
Publicado no:Sci Signal
Main Authors: Saleiro, Diana, Blyth, Gavin T., Kosciuczuk, Ewa M., Ozark, Patrick A., Majchrzak-Kita, Beata, Arslan, Ahmet D., Fischietti, Mariafausta, Reddy, Neha K., Horvath, Curt M., Davis, Roger J., Fish, Eleanor N., Platanias, Leonidas C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6684240/
https://ncbi.nlm.nih.gov/pubmed/30459284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aap9921
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