Effects of p53-knockout in vascular smooth muscle cells on atherosclerosis in mice

In vitro and in vivo evidence has indicated that the tumor suppressor, p53, may play a significant role in the regulation of atherosclerotic plaque formation. In vivo studies using global knockout mice models, however, have generated inconclusive results that do not address the roles of p53 in vario...

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Bibliographic Details
Published in:PLoS One
Main Authors: Cao, Richard Yang, Eves, Robert, Jia, Lilly, Funk, Colin D., Jia, Zongchao, Mak, Alan S.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5376331/
https://ncbi.nlm.nih.gov/pubmed/28362832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0175061
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