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Txnip Ablation Reduces Vascular Smooth Muscle Cell Inflammation and Ameliorates Atherosclerosis in Apolipoprotein E Knockout Mice
OBJECTIVE: Inflammation of vascular smooth muscle cells (VSMC) is intimately linked to atherosclerosis and other vascular inflammatory disease. Thioredoxin interacting protein (Txnip) is a key regulator of cellular sulfhydryl redox and a mediator of inflammasome activation. The goals of the present...
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Publicado no: | Atherosclerosis |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4509824/ https://ncbi.nlm.nih.gov/pubmed/26062991 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2015.05.020 |
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