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Txnip Ablation Reduces Vascular Smooth Muscle Cell Inflammation and Ameliorates Atherosclerosis in Apolipoprotein E Knockout Mice

OBJECTIVE: Inflammation of vascular smooth muscle cells (VSMC) is intimately linked to atherosclerosis and other vascular inflammatory disease. Thioredoxin interacting protein (Txnip) is a key regulator of cellular sulfhydryl redox and a mediator of inflammasome activation. The goals of the present...

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Bibliografische gegevens
Gepubliceerd in:Atherosclerosis
Hoofdauteurs: Byon, Chang Hyun, Han, Tieyan, Wu, Judy, Hui, Simon T.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4509824/
https://ncbi.nlm.nih.gov/pubmed/26062991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2015.05.020
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