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p53 regulation of podosome formation and cellular invasion in vascular smooth muscle cells

The p53 transcription factor, discovered in 1979,1,2 is well known as a potent suppressor of tumor development by inhibiting cell cycle progression, and promoting senescence or apoptosis, when the genome is compromised or under oncogenic stress.3 Accumulating evidence has pointed to an alternative r...

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Detalles Bibliográficos
Autor principal: Mak, Alan S
Formato: Artigo
Lenguaje:Inglês
Publicado: Landes Bioscience 2011
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084980/
https://ncbi.nlm.nih.gov/pubmed/21164280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cam.5.2.14375
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