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p53 Down Regulates PDGF-Induced Formation of Circular Dorsal Ruffles in Rat Aortic Smooth Muscle Cells

The tumor suppressor, p53, negatively regulates cell migration and invasion in addition to its role in apoptosis, cell cycle regulation and senescence. Here, we study the roles of p53 in PDGF-induced circular dorsal ruffle (CDR) formation in rat aortic smooth muscle (RASM) cells. In primary and immo...

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Detalhes bibliográficos
Main Authors: Payne, Laura J., Eves, Robert L., Jia, Lilly, Mak, Alan S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4172730/
https://ncbi.nlm.nih.gov/pubmed/25247424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0108257
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