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Effects of p53-knockout in vascular smooth muscle cells on atherosclerosis in mice

In vitro and in vivo evidence has indicated that the tumor suppressor, p53, may play a significant role in the regulation of atherosclerotic plaque formation. In vivo studies using global knockout mice models, however, have generated inconclusive results that do not address the roles of p53 in vario...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Cao, Richard Yang, Eves, Robert, Jia, Lilly, Funk, Colin D., Jia, Zongchao, Mak, Alan S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5376331/
https://ncbi.nlm.nih.gov/pubmed/28362832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0175061
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