Φορτώνει......
AKT-mediated stabilization of histone methyltransferase WHSC1 promotes prostate cancer metastasis
Loss of phosphatase and tensin homolog (PTEN) and activation of the PI3K/AKT signaling pathway are hallmarks of prostate cancer (PCa). However, these alterations alone are insufficient for cells to acquire metastatic traits. Here, we have shown that the histone dimethyl transferase WHSC1 critically...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | J Clin Invest |
|---|---|
| Κύριοι συγγραφείς: | , , , , , , , , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American Society for Clinical Investigation
2017
|
| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5373871/ https://ncbi.nlm.nih.gov/pubmed/28319045 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI91144 |
| Ετικέτες: |
Προσθήκη ετικέτας
Δεν υπάρχουν, Καταχωρήστε ετικέτα πρώτοι!
|