BAP1 inhibits the ER stress gene regulatory network and modulates metabolic stress response

The endoplasmic reticulum (ER) is classically linked to metabolic homeostasis via the activation of unfolded protein response (UPR), which is instructed by multiple transcriptional regulatory cascades. BRCA1 associated protein 1 (BAP1) is a tumor suppressor with de-ubiquitinating enzyme activity and...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Dai, Fangyan, Lee, Hyemin, Zhang, Yilei, Zhuang, Li, Yao, Hui, Xi, Yuanxin, Xiao, Zhen-Dong, You, M. James, Li, Wei, Su, Xiaoping, Gan, Boyi
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2017
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5373337/
https://ncbi.nlm.nih.gov/pubmed/28275095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1619588114
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