BAP1 inhibits the ER stress gene regulatory network and modulates metabolic stress response

The endoplasmic reticulum (ER) is classically linked to metabolic homeostasis via the activation of unfolded protein response (UPR), which is instructed by multiple transcriptional regulatory cascades. BRCA1 associated protein 1 (BAP1) is a tumor suppressor with de-ubiquitinating enzyme activity and...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Dai, Fangyan, Lee, Hyemin, Zhang, Yilei, Zhuang, Li, Yao, Hui, Xi, Yuanxin, Xiao, Zhen-Dong, You, M. James, Li, Wei, Su, Xiaoping, Gan, Boyi
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5373337/
https://ncbi.nlm.nih.gov/pubmed/28275095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1619588114
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