BAF180 regulates cellular senescence and hematopoietic stem cell homeostasis through p21

BAF180 (also called PBRM1), a subunit of the SWI/SNF complex, plays critical roles in the regulation of chromatin remodeling and gene transcription, and is frequently mutated in several human cancers. However, the role of mammalian BAF180 in tumor suppression and tissue maintenance in vivo remains l...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Lee, Hyemin, Dai, Fangyan, Zhuang, Li, Xiao, Zhen-Dong, Kim, Jongchan, Zhang, Yilei, Ma, Li, You, M. James, Wang, Zhong, Gan, Boyi
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper: Gerotarget (Focus on Aging)
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4991371/
https://ncbi.nlm.nih.gov/pubmed/26992241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8102
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