BAF180 regulates cellular senescence and hematopoietic stem cell homeostasis through p21

BAF180 (also called PBRM1), a subunit of the SWI/SNF complex, plays critical roles in the regulation of chromatin remodeling and gene transcription, and is frequently mutated in several human cancers. However, the role of mammalian BAF180 in tumor suppression and tissue maintenance in vivo remains l...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Oncotarget
Autores principales: Lee, Hyemin, Dai, Fangyan, Zhuang, Li, Xiao, Zhen-Dong, Kim, Jongchan, Zhang, Yilei, Ma, Li, You, M. James, Wang, Zhong, Gan, Boyi
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2016
Materias:
Research Paper: Gerotarget (Focus on Aging)
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4991371/
https://ncbi.nlm.nih.gov/pubmed/26992241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8102
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares