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BAP1 suppresses tumor development by inducing ferroptosis upon SLC7A11 repression
The tumor suppressor BRCA1-associated protein 1 (BAP1) is a deubiquitinase that removes histone 2A ubiquitination. How BAP1 suppresses tumor development remains elusive. Our recent study identified the cystine transporter solute carrier family 7 member 11 (SLC7A11) as a critical BAP1 target, and sho...
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| Publicado no: | Mol Cell Oncol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6370386/ https://ncbi.nlm.nih.gov/pubmed/30788415 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2018.1536845 |
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