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Regulation of H2A ubiquitination and SLC7A11 expression by BAP1 and PRC1
SLC7A11 (or xCT) imports extracellular cystine into cells to promote glutathione synthesis, thus inhibiting ferroptosis. SLC7A11 expression is tightly controlled in normal cells and its dysregulation results in aberrant expression of SLC7A11 in human cancers. We recently discovered that tumor suppre...
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| Publicado no: | Cell Cycle |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6527290/ https://ncbi.nlm.nih.gov/pubmed/30907299 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2019.1597506 |
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