BAF180 regulates cellular senescence and hematopoietic stem cell homeostasis through p21

BAF180 (also called PBRM1), a subunit of the SWI/SNF complex, plays critical roles in the regulation of chromatin remodeling and gene transcription, and is frequently mutated in several human cancers. However, the role of mammalian BAF180 in tumor suppression and tissue maintenance in vivo remains l...

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Vydáno v:Oncotarget
Hlavní autoři: Lee, Hyemin, Dai, Fangyan, Zhuang, Li, Xiao, Zhen-Dong, Kim, Jongchan, Zhang, Yilei, Ma, Li, You, M. James, Wang, Zhong, Gan, Boyi
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
Research Paper: Gerotarget (Focus on Aging)
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4991371/
https://ncbi.nlm.nih.gov/pubmed/26992241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8102
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