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The challenges of tumor genetic diversity

We review and discuss the implications of genomic analyses documenting the diversity of tumors, both among patients and within individual tumors. Genetic diversity among solid tumors limits targeted therapies, as few mutations that drive tumors are both targetable and at high prevalence. Many more d...

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Detalhes bibliográficos
Publicado no:Cancer
Main Authors: Mroz, Edmund A., Rocco, James W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5370554/
https://ncbi.nlm.nih.gov/pubmed/27861749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.30430
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