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Intra-tumor heterogeneity could inform the use and type of postoperative adjuvant therapy in head and neck squamous cell carcinoma

BACKGROUND: Following surgery for head and neck squamous cell carcinoma (HNSCC), decisions about adjuvant radiotherapy (RT) or chemoradiotherapy (CRT) are based on staging and the presence of high-risk pathology. As higher mutant-allele tumor heterogeneity (MATH, a measure of intra-tumor genetic het...

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Detalhes bibliográficos
Publicado no:Cancer
Main Authors: Mroz, Edmund A., Patel, Krupal B., Rocco, James W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7160035/
https://ncbi.nlm.nih.gov/pubmed/32083741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.32742
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