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High intra-tumor genetic heterogeneity is related to worse outcome in head and neck squamous cell carcinoma
BACKGROUND: Although the presence of genetic heterogeneity within individual patients’ tumors is established, it is unclear whether greater heterogeneity predicts worse outcome. A quantitative measure of genetic heterogeneity based on next-generation sequencing (NGS) data, mutant-allele tumor hetero...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3735618/ https://ncbi.nlm.nih.gov/pubmed/23696076 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.28150 |
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