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Intra-tumor Genetic Heterogeneity and Mortality in Head and Neck Cancer: Analysis of Data from The Cancer Genome Atlas

BACKGROUND: Although the involvement of intra-tumor genetic heterogeneity in tumor progression, treatment resistance, and metastasis is established, genetic heterogeneity is seldom examined in clinical trials or practice. Many studies of heterogeneity have had prespecified markers for tumor subpopul...

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Detalhes bibliográficos
Publicado no:PLoS Med
Main Authors: Mroz, Edmund A., Tward, Aaron M., Hammon, Rebecca J., Ren, Yin, Rocco, James W.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4323109/
https://ncbi.nlm.nih.gov/pubmed/25668320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.1001786
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