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Intra-tumor Genetic Heterogeneity and Mortality in Head and Neck Cancer: Analysis of Data from The Cancer Genome Atlas

BACKGROUND: Although the involvement of intra-tumor genetic heterogeneity in tumor progression, treatment resistance, and metastasis is established, genetic heterogeneity is seldom examined in clinical trials or practice. Many studies of heterogeneity have had prespecified markers for tumor subpopul...

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Udgivet i:PLoS Med
Main Authors: Mroz, Edmund A., Tward, Aaron M., Hammon, Rebecca J., Ren, Yin, Rocco, James W.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4323109/
https://ncbi.nlm.nih.gov/pubmed/25668320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.1001786
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