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MATH, a novel measure of intratumor genetic heterogeneity, is high in poor-outcome classes of head and neck squamous cell carcinoma

OBJECTIVES: Differences among cancer cells within a tumor are important in tumorigenesis and treatment resistance, yet no measure of intratumor heterogeneity is suitable for routine application. We developed a quantitative measure of intratumor genetic heterogeneity, based on differences among mutat...

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Bibliografski detalji
Glavni autori: Mroz, Edmund A., Rocco, James W.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3570658/
https://ncbi.nlm.nih.gov/pubmed/23079694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.oraloncology.2012.09.007
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