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Glutamate-dependent ectodomain shedding of neuregulin-1 type II precursors in rat forebrain neurons
The neurotrophic factor neuregulin 1 (NRG1) regulates neuronal development, glial differentiation, and excitatory synapse maturation. NRG1 is synthesized as a membrane-anchored precursor and is then liberated by proteolytic processing or exocytosis. Mature NRG1 then binds to its receptors expressed...
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| 出版年: | PLoS One |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5370147/ https://ncbi.nlm.nih.gov/pubmed/28350885 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0174780 |
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