Prostaglandin E(2) Mediates Immunosuppression in Acutely Decompensated Cirrhosis

Patients with advanced cirrhosis experience frequent infections leading to sepsis, which carries high mortality. While innate immune dysfunction underlies this vulnerability, the precise cause remains elusive. We found prostaglandin (PGE(2)) elevated in acutely decompensated (AD) patients at immunos...

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Detalhes bibliográficos
Publicado no:Nat Med
Main Authors: O’Brien, Alastair J., Fullerton, James N., Massey, Karen A., Auld, Grace, Sewell, Gavin, James, Sarah, Newson, Justine, Karra, Effie, Winstanley, Alison, Alazawi, William, Garcia-Marquez, Rita, Cordoba, Juan, Nicolaou, Anna, Gilroy, Derek W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5369639/
https://ncbi.nlm.nih.gov/pubmed/24728410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3516
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