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Prostaglandin E(2) Mediates Immunosuppression in Acutely Decompensated Cirrhosis

Patients with advanced cirrhosis experience frequent infections leading to sepsis, which carries high mortality. While innate immune dysfunction underlies this vulnerability, the precise cause remains elusive. We found prostaglandin (PGE(2)) elevated in acutely decompensated (AD) patients at immunos...

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Bibliographische Detailangaben
Veröffentlicht in:Nat Med
Hauptverfasser: O’Brien, Alastair J., Fullerton, James N., Massey, Karen A., Auld, Grace, Sewell, Gavin, James, Sarah, Newson, Justine, Karra, Effie, Winstanley, Alison, Alazawi, William, Garcia-Marquez, Rita, Cordoba, Juan, Nicolaou, Anna, Gilroy, Derek W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5369639/
https://ncbi.nlm.nih.gov/pubmed/24728410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3516
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