Prostaglandin E(2) Mediates Immunosuppression in Acutely Decompensated Cirrhosis

Patients with advanced cirrhosis experience frequent infections leading to sepsis, which carries high mortality. While innate immune dysfunction underlies this vulnerability, the precise cause remains elusive. We found prostaglandin (PGE(2)) elevated in acutely decompensated (AD) patients at immunos...

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Bibliografiske detaljer
Udgivet i:	Nat Med
Main Authors:	O’Brien, Alastair J., Fullerton, James N., Massey, Karen A., Auld, Grace, Sewell, Gavin, James, Sarah, Newson, Justine, Karra, Effie, Winstanley, Alison, Alazawi, William, Garcia-Marquez, Rita, Cordoba, Juan, Nicolaou, Anna, Gilroy, Derek W.
Format:	Artigo
Sprog:	Inglês
Udgivet:	2014
Fag:	Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC5369639/ https://ncbi.nlm.nih.gov/pubmed/24728410 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3516
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Prostaglandin E(2) Mediates Immunosuppression in Acutely Decompensated Cirrhosis

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