Prostaglandin E(2) Mediates Immunosuppression in Acutely Decompensated Cirrhosis

Patients with advanced cirrhosis experience frequent infections leading to sepsis, which carries high mortality. While innate immune dysfunction underlies this vulnerability, the precise cause remains elusive. We found prostaglandin (PGE(2)) elevated in acutely decompensated (AD) patients at immunos...

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Publicado en:Nat Med
Main Authors: O’Brien, Alastair J., Fullerton, James N., Massey, Karen A., Auld, Grace, Sewell, Gavin, James, Sarah, Newson, Justine, Karra, Effie, Winstanley, Alison, Alazawi, William, Garcia-Marquez, Rita, Cordoba, Juan, Nicolaou, Anna, Gilroy, Derek W.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5369639/
https://ncbi.nlm.nih.gov/pubmed/24728410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3516
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