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Crystal structure of TBC1D15 GTPase‐activating protein (GAP) domain and its activity on Rab GTPases

TBC1D15 belongs to the TBC (Tre‐2/Bub2/Cdc16) domain family and functions as a GTPase‐activating protein (GAP) for Rab GTPases. So far, the structure of TBC1D15 or the TBC1D15·Rab complex has not been determined, thus, its catalytic mechanism on Rab GTPases is still unclear. In this study, we solved...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Protein Sci
Asıl Yazarlar: Chen, Yan‐Na, Gu, Xin, Zhou, X. Edward, Wang, Weidong, Cheng, Dandan, Ge, Yinghua, Ye, Fei, Xu, H. Eric, Lv, Zhengbing
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5368074/
https://ncbi.nlm.nih.gov/pubmed/28168758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3132
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