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Crystal structure of TBC1D15 GTPase‐activating protein (GAP) domain and its activity on Rab GTPases
TBC1D15 belongs to the TBC (Tre‐2/Bub2/Cdc16) domain family and functions as a GTPase‐activating protein (GAP) for Rab GTPases. So far, the structure of TBC1D15 or the TBC1D15·Rab complex has not been determined, thus, its catalytic mechanism on Rab GTPases is still unclear. In this study, we solved...
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| Pubblicato in: | Protein Sci |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5368074/ https://ncbi.nlm.nih.gov/pubmed/28168758 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3132 |
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