A fragment activity assay reveals the key residues of TBC1D15 GTPase-activating protein (GAP) in Chiloscyllium plagiosum

BACKGROUND: GTPase-activating proteins (GAPs) with a TBC (Tre-2/Bub2/Cdc16) domain architecture serve as negative regulators of Rab GTPases. The related crystal structure has been studied and reported by other members of our research group in 2017 (Chen et al. in Protein Sci 26(4):834–846, 2017). Th...

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Bibliografski detalji
Izdano u:BMC Mol Biol
Glavni autori: Jin, Yangyang, Lin, Guodong, Chen, Yanna, Ge, Yinghua, Liang, Ruofeng, Wu, Jia, Chen, Jianqing, Wang, Dan, Shi, Hengbo, Fei, Hui, Lv, Zhengbing
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2019
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6373008/
https://ncbi.nlm.nih.gov/pubmed/30755162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12867-019-0122-2
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