A fragment activity assay reveals the key residues of TBC1D15 GTPase-activating protein (GAP) in Chiloscyllium plagiosum

BACKGROUND: GTPase-activating proteins (GAPs) with a TBC (Tre-2/Bub2/Cdc16) domain architecture serve as negative regulators of Rab GTPases. The related crystal structure has been studied and reported by other members of our research group in 2017 (Chen et al. in Protein Sci 26(4):834–846, 2017). Th...

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Xehetasun bibliografikoak
Argitaratua izan da:BMC Mol Biol
Egile Nagusiak: Jin, Yangyang, Lin, Guodong, Chen, Yanna, Ge, Yinghua, Liang, Ruofeng, Wu, Jia, Chen, Jianqing, Wang, Dan, Shi, Hengbo, Fei, Hui, Lv, Zhengbing
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2019
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6373008/
https://ncbi.nlm.nih.gov/pubmed/30755162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12867-019-0122-2
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