A fragment activity assay reveals the key residues of TBC1D15 GTPase-activating protein (GAP) in Chiloscyllium plagiosum

BACKGROUND: GTPase-activating proteins (GAPs) with a TBC (Tre-2/Bub2/Cdc16) domain architecture serve as negative regulators of Rab GTPases. The related crystal structure has been studied and reported by other members of our research group in 2017 (Chen et al. in Protein Sci 26(4):834–846, 2017). Th...

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Detalhes bibliográficos
Publicado no:BMC Mol Biol
Main Authors: Jin, Yangyang, Lin, Guodong, Chen, Yanna, Ge, Yinghua, Liang, Ruofeng, Wu, Jia, Chen, Jianqing, Wang, Dan, Shi, Hengbo, Fei, Hui, Lv, Zhengbing
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6373008/
https://ncbi.nlm.nih.gov/pubmed/30755162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12867-019-0122-2
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