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Crystal structure of TBC1D15 GTPase‐activating protein (GAP) domain and its activity on Rab GTPases

TBC1D15 belongs to the TBC (Tre‐2/Bub2/Cdc16) domain family and functions as a GTPase‐activating protein (GAP) for Rab GTPases. So far, the structure of TBC1D15 or the TBC1D15·Rab complex has not been determined, thus, its catalytic mechanism on Rab GTPases is still unclear. In this study, we solved...

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Bibliografske podrobnosti
izdano v:Protein Sci
Main Authors: Chen, Yan‐Na, Gu, Xin, Zhou, X. Edward, Wang, Weidong, Cheng, Dandan, Ge, Yinghua, Ye, Fei, Xu, H. Eric, Lv, Zhengbing
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5368074/
https://ncbi.nlm.nih.gov/pubmed/28168758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3132
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