Crystal structure of TBC1D15 GTPase‐activating protein (GAP) domain and its activity on Rab GTPases

TBC1D15 belongs to the TBC (Tre‐2/Bub2/Cdc16) domain family and functions as a GTPase‐activating protein (GAP) for Rab GTPases. So far, the structure of TBC1D15 or the TBC1D15·Rab complex has not been determined, thus, its catalytic mechanism on Rab GTPases is still unclear. In this study, we solved...

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Bibliografiset tiedot
Julkaisussa:Protein Sci
Päätekijät: Chen, Yan‐Na, Gu, Xin, Zhou, X. Edward, Wang, Weidong, Cheng, Dandan, Ge, Yinghua, Ye, Fei, Xu, H. Eric, Lv, Zhengbing
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2017
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Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5368074/
https://ncbi.nlm.nih.gov/pubmed/28168758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3132
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