CDDO-Me reveals USP7 as a novel target in ovarian cancer cells

Deubiquitinating enzyme USP7 has been involved in the pathogenesis and progression of several cancers. Targeting USP7 is becoming an attractive strategy for cancer therapy. In this study, we identified synthetic triterpenoid C-28 methyl ester of 2-cyano-3, 12-dioxoolen-1, 9-dien-28-oic acid (CDDO-Me...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Qin, Dongjun, Wang, Weiwei, Lei, Hu, Luo, Hao, Cai, Haiyan, Tang, Caixia, Wu, Yunzhao, Wang, Yingying, Jin, Jin, Xiao, Weilie, Wang, Tongdan, Ma, Chunmin, Xu, Hanzhang, Zhang, Jinfu, Gao, Fenghou, Wu, Ying-Li
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363571/
https://ncbi.nlm.nih.gov/pubmed/27780924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12801
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