Synthesis and Anticancer Activity of CDDO and CDDO-Me, Two Derivatives of Natural Triterpenoids

Triterpenoids are natural compounds synthesized by plants through cyclization of squalene, known for their weak anti-inflammatory activity. 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid (CDDO), and its C28 modified derivative, methyl-ester (CDDO-Me, also known as bardoxolone methyl), are two syn...

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Bibliografiske detaljer
Udgivet i:Molecules
Main Authors: Borella, Rebecca, Forti, Luca, Gibellini, Lara, De Gaetano, Anna, De Biasi, Sara, Nasi, Milena, Cossarizza, Andrea, Pinti, Marcello
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6891335/
https://ncbi.nlm.nih.gov/pubmed/31766211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24224097
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