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Impaired Mitochondrial Morphology and Functionality in Lonp1(wt/−) Mice
LONP1 is a nuclear-encoded mitochondrial protease crucial for organelle homeostasis; mutations of LONP1 have been associated with Cerebral, Ocular, Dental, Auricular, and Skeletal anomalies (CODAS) syndrome. To clarify the role of LONP1 in vivo, we generated a mouse model in which Lonp1 was ablated....
Guardat en:
| Publicat a: | J Clin Med |
|---|---|
| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
MDPI
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7355737/ https://ncbi.nlm.nih.gov/pubmed/32521756 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm9061783 |
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