Momordin Ic, a new natural SENP1 inhibitor, inhibits prostate cancer cell proliferation

SUMO-specific protease 1 (SENP1), a member of the de-SUMOylation protease family, is elevated in prostate cancer (PCa) cells and is involved in PCa pathogenesis. Momordin Ιc (Mc), a natural pentacyclic triterpenoid, inhibited SENP1 in vitro, as reflected by reduced SENP1C-induced cleavage of SUMO2-Δ...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Oncotarget
Principais autores: Wu, Jingjing, Lei, Hu, Zhang, Jinfu, Chen, Xiangyun, Tang, Caixia, Wang, Weiwei, Xu, Hanzhang, Xiao, Weilie, Gu, Wenli, Wu, Yingli
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312290/
https://ncbi.nlm.nih.gov/pubmed/27449295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10636
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registros relacionados