CDDO-Me reveals USP7 as a novel target in ovarian cancer cells

Deubiquitinating enzyme USP7 has been involved in the pathogenesis and progression of several cancers. Targeting USP7 is becoming an attractive strategy for cancer therapy. In this study, we identified synthetic triterpenoid C-28 methyl ester of 2-cyano-3, 12-dioxoolen-1, 9-dien-28-oic acid (CDDO-Me...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Qin, Dongjun, Wang, Weiwei, Lei, Hu, Luo, Hao, Cai, Haiyan, Tang, Caixia, Wu, Yunzhao, Wang, Yingying, Jin, Jin, Xiao, Weilie, Wang, Tongdan, Ma, Chunmin, Xu, Hanzhang, Zhang, Jinfu, Gao, Fenghou, Wu, Ying-Li
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363571/
https://ncbi.nlm.nih.gov/pubmed/27780924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12801
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