ROS Mediate Proapoptotic and Antisurvival Activity of Oleanane Triterpenoid CDDO-Me in Ovarian Cancer Cells

Oleanane triterpenoids are broad-spectrum antiproliferative and proapoptotic agents. In this study, we investigated whether reactive oxygen species (ROS) play a role in the antitumor activity of methyl-2-cyano-3, 12-dioxooleana-1, 9(11)-dien-28-oate (CDDO-Me) in OVCAR-5 and MDAH 2774 ovarian cancer...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: GAO, XIAOHUA, LIU, YONGBO, DEEB, DORRAH, LIU, PATRICIA, LIU, ANNIE, ARBAB, ALI S., GAUTAM, SUBHASH C.
Formato: Artigo
Idioma:Inglês
Publicado: 2013
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711076/
https://ncbi.nlm.nih.gov/pubmed/23267148
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares