ROS Mediate Proapoptotic and Antisurvival Activity of Oleanane Triterpenoid CDDO-Me in Ovarian Cancer Cells

Oleanane triterpenoids are broad-spectrum antiproliferative and proapoptotic agents. In this study, we investigated whether reactive oxygen species (ROS) play a role in the antitumor activity of methyl-2-cyano-3, 12-dioxooleana-1, 9(11)-dien-28-oate (CDDO-Me) in OVCAR-5 and MDAH 2774 ovarian cancer...

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Main Authors: GAO, XIAOHUA, LIU, YONGBO, DEEB, DORRAH, LIU, PATRICIA, LIU, ANNIE, ARBAB, ALI S., GAUTAM, SUBHASH C.
格式: Artigo
語言:Inglês
出版: 2013
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711076/
https://ncbi.nlm.nih.gov/pubmed/23267148
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