Impairment of fetal hematopoietic stem cell function in the absence of Fancd2

Fanconi Anemia (FA), results from mutations in genes necessary for DNA damage repair and often leads to progressive bone marrow failure. Although the exhaustion of the bone marrow leads to cytopenias in FA patients as they age, evidence from human FA and mouse model fetal livers suggests hematopoiet...

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Vydáno v:Exp Hematol
Hlavní autoři: Suzuki, Sakiko, Racine, Ronny R., Manalo, Nathan A., Cantor, Sharon B., Raffel, Glen D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5362321/
https://ncbi.nlm.nih.gov/pubmed/27915139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2016.11.006
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