Hematopoietic Stem Cell Defects in Mice with Deficiency of Fancd2 or Usp1

Fanconi anemia (FA) is a human genetic disease characterized by a DNA repair defect and progressive bone marrow failure. Central events in the FA pathway are the monoubiquitination of the Fancd2 protein and the removal of ubiquitin by the deubiquitinating enzyme, Usp1. Here, we have investigated the...

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Detaylı Bibliyografya
Asıl Yazarlar: Parmar, Kalindi, Kim, Jungmin, Sykes, Stephen M., Shimamura, Akiko, Stuckert, Patricia, Zhu, Kaya, Hamilton, Abigail, Deloach, Mary Kathryn, Kutok, Jeffery L., Akashi, Koichi, Gilliland, D. Gary, D’andrea, Alan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2910804/
https://ncbi.nlm.nih.gov/pubmed/20506303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.437
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