Hematopoietic Stem Cell Defects in Mice with Deficiency of Fancd2 or Usp1

Fanconi anemia (FA) is a human genetic disease characterized by a DNA repair defect and progressive bone marrow failure. Central events in the FA pathway are the monoubiquitination of the Fancd2 protein and the removal of ubiquitin by the deubiquitinating enzyme, Usp1. Here, we have investigated the...

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Autors principals: Parmar, Kalindi, Kim, Jungmin, Sykes, Stephen M., Shimamura, Akiko, Stuckert, Patricia, Zhu, Kaya, Hamilton, Abigail, Deloach, Mary Kathryn, Kutok, Jeffery L., Akashi, Koichi, Gilliland, D. Gary, D’andrea, Alan
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2910804/
https://ncbi.nlm.nih.gov/pubmed/20506303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.437
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