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Impairment of fetal hematopoietic stem cell function in the absence of Fancd2
Fanconi Anemia (FA), results from mutations in genes necessary for DNA damage repair and often leads to progressive bone marrow failure. Although the exhaustion of the bone marrow leads to cytopenias in FA patients as they age, evidence from human FA and mouse model fetal livers suggests hematopoiet...
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| Опубликовано в: : | Exp Hematol |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5362321/ https://ncbi.nlm.nih.gov/pubmed/27915139 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2016.11.006 |
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