Загрузка...

A system for coordinated analysis of translational readthrough and nonsense-mediated mRNA decay

The nonsense-mediated mRNA decay (NMD) pathway degrades mRNAs containing premature termination codons, limiting the expression of potentially deleterious truncated proteins. This activity positions the pathway as a regulator of the severity of genetic diseases caused by nonsense mutations. Because m...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :PLoS One
Главные авторы: Baker, Stacey L., Hogg, J. Robert
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5360307/
https://ncbi.nlm.nih.gov/pubmed/28323884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0173980
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!