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Nonsense-Mediated Decay of Human HEXA mRNA
Nonsense-mediated mRNA decay (NMD), the loss of mRNAs carrying premature stop codons, is a process by which cells recognize and degrade nonsense mRNAs to prevent possibly toxic effects of truncated peptides. Most mammalian nonsense mRNAs are degraded while associated with the nucleus, but a few are...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Microbiology
2001
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC87273/ https://ncbi.nlm.nih.gov/pubmed/11463833 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.16.5512-5519.2001 |
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