Nonsense-Mediated Decay of Human HEXA mRNA

Nonsense-mediated mRNA decay (NMD), the loss of mRNAs carrying premature stop codons, is a process by which cells recognize and degrade nonsense mRNAs to prevent possibly toxic effects of truncated peptides. Most mammalian nonsense mRNAs are degraded while associated with the nucleus, but a few are...

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Bibliographic Details
Main Authors: Rajavel, Kavitha S., Neufeld, Elizabeth F.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2001
Subjects:
Gene Expression
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC87273/
https://ncbi.nlm.nih.gov/pubmed/11463833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.16.5512-5519.2001
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