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Nonsense-Mediated mRNA Decay Begins Where Translation Ends
Nonsense-mediated mRNA decay (NMD) is arguably the best-studied eukaryotic messenger RNA (mRNA) surveillance pathway, yet fundamental questions concerning the molecular mechanism of target RNA selection remain unsolved. Besides degrading defective mRNAs harboring premature termination codons (PTCs),...
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| Publicado no: | Cold Spring Harb Perspect Biol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6360860/ https://ncbi.nlm.nih.gov/pubmed/29891560 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a032862 |
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