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Nonsense‐mediated mRNA decay: novel mechanistic insights and biological impact
Nonsense‐mediated mRNA decay (NMD) was originally coined to define a quality control mechanism that targets mRNAs with truncated open reading frames due to the presence of a premature termination codon. Meanwhile, it became clear that NMD has a much broader impact on gene expression and additional b...
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| Veröffentlicht in: | Wiley Interdiscip Rev RNA |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
John Wiley & Sons, Inc.
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6680220/ https://ncbi.nlm.nih.gov/pubmed/27173476 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/wrna.1357 |
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