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Nonsense‐mediated mRNA decay: novel mechanistic insights and biological impact

Nonsense‐mediated mRNA decay (NMD) was originally coined to define a quality control mechanism that targets mRNAs with truncated open reading frames due to the presence of a premature termination codon. Meanwhile, it became clear that NMD has a much broader impact on gene expression and additional b...

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Dades bibliogràfiques
Publicat a:Wiley Interdiscip Rev RNA
Autors principals: Karousis, Evangelos D., Nasif, Sofia, Mühlemann, Oliver
Format: Artigo
Idioma:Inglês
Publicat: John Wiley & Sons, Inc. 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6680220/
https://ncbi.nlm.nih.gov/pubmed/27173476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/wrna.1357
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