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A system for coordinated analysis of translational readthrough and nonsense-mediated mRNA decay
The nonsense-mediated mRNA decay (NMD) pathway degrades mRNAs containing premature termination codons, limiting the expression of potentially deleterious truncated proteins. This activity positions the pathway as a regulator of the severity of genetic diseases caused by nonsense mutations. Because m...
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| 發表在: | PLoS One |
|---|---|
| Main Authors: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Public Library of Science
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5360307/ https://ncbi.nlm.nih.gov/pubmed/28323884 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0173980 |
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